Scleromyxedema: Successful treatment with IVIg and lenalidomide

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Treatment of scleromyxedema with IVIg

Results An 18 year old male presented with a rash of three weeks duration. Soon after the rash appeared, he developed pain and swelling of the right hand, as well as numbness and tingling of the right forearm. A recreational weight lifter, he noticed progressively decreasing stamina and amount of weight that he could lift. Swelling of the eyelids and bridge of nose prompted treatment for an all...

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Scleromyxedema: a case series highlighting long-term outcomes of treatment with intravenous immunoglobulin (IVIG).

Scleromyxedema is a rare disease characterized by mucin deposition in skin and other organs and the production of a monoclonal IgG protein. Herein we describe our experience with a series of patients with this condition and specifically focus on the use of intravenous immunoglobulin (IVIG) for long-term management. We retrospectively reviewed the clinical manifestations of 10 patients evaluated...

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A case of scleromyxedema responding to lenalidomide and dexamethasone

The presence of corns can be considered as a marker for ulceration as the mechanical forces that cause corns and Calluses can also rupture portions of subcutaneous vascular plexus. In healthy patients this may be of minimal significance, but in patients with connective tissue disease it may herald extensive skin ulceration or vasculitis.[5] Thus, corns can be regarded as a sign of the onslaught...

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Scleromyxedema with Subcutaneous Nodules: Successful Treatment with Thalidomide and Intravenous Immunoglobulin

Scleromyxedema is a rare cutaneous mucinosis, usually presenting with generalized papular eruption and sclerodermoid induration, monoclonal gammopathy and systemic manifestations. An atypical clinical presentation with cutaneous and subcutaneous nodules has been reported rarely. In recent years, intravenous immunoglobulin (IVIg) appears to be the therapy of choice for scleromyxedema. Treatment ...

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ژورنال

عنوان ژورنال: Internet Journal of Rheumatology and Clinical Immunology

سال: 2018

ISSN: 2320-7221

DOI: 10.15305/ijrci/v6i1/242